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Anyone with bio-chem knowledge in here?
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1
#1
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My friend is doing a project about Allergy, but he is struggling to describe 1 question in 5 pages, which is:

"Analyze the chemical structures of histamine and following antihistamine plus how theyre bound to the h1-receptor."
The antihistamines are: Doxepin, Doxylamin and Cetirizin.

Any advice on how can you describe all of this in 5 pages? Examples are welcome as well.

My friend is doing a project about Allergy, but he is struggling to describe 1 question in 5 pages, which is:

"Analyze the chemical structures of histamine and following antihistamine plus how theyre bound to the h1-receptor."
The antihistamines are: Doxepin, Doxylamin and Cetirizin.

Any advice on how can you describe all of this in 5 pages? Examples are welcome as well.
2
#2
7 Frags +

I don't think anybody on tf.tv is going to do your five page homework assignment for you... But by "analyze the chemical structures", I would talk about functional groups, polarity, maybe steric hindrance if its relevant, briefly talk about their biosynthesis if you need filler. Mainly any properties that affect their binding to h1-receptor the greatest, which will most likely be the functional groups on histamine/anti-histamine and the active site of h1-receptor. You should use reports and scientific journal articles for the reaction mechanisms, "further reading" section on wikipedia is not a bad place to start looking for references

I don't think anybody on tf.tv is going to do your five page homework assignment for you... But by "analyze the chemical structures", I would talk about functional groups, polarity, maybe steric hindrance if its relevant, briefly talk about their biosynthesis if you need filler. Mainly any properties that affect their binding to h1-receptor the greatest, which will most likely be the functional groups on histamine/anti-histamine and the active site of h1-receptor. You should use reports and scientific journal articles for the reaction mechanisms, "further reading" section on wikipedia is not a bad place to start looking for references
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