VisThere aren't any settings that will mirracly improve your ping.
That's not the point of the question though...
He's asking for what would give him the best hit registration / most enjoyable experience.
Regardless of what class you play.
cl_updaterate 66
cl_cmdrate 65
according to mastercoms cl_cmdrate is set lower than cl_updaterate to have smoothing be applied to server updates and not client updates *my understanding of this could be wrong*
If you main a projectile/particle class (Soldier, Demo, Pyro and Medic)
cl_interp_ratio 1
cl_interp .0152 (a value of 0 would be fine as well)
If you main a hitscan class (Scout, Heavy, Sniper and Spy)
cl_interp_ratio 2 (possibly higher)
cl_interp .0228 (possibly higher but this should work fine)
or (for basically the same thing)
cl_interp_ratio 3
cl_interp .0152
I didn't add Engineer to either list cause I can see an argument both ways. On 1 hand a low interp value would be better for Rescue Ranger + less latency to hitting a sentry with a wrench + less latency to start building on the other hand a higher interp setting would give better overall hit registration for PvP melee and hitscan weapons.
mastercomfig seems to generally recommend these other settings as well
net_compresspackets 1
net_compresspackets_minsize 128
rate 196608 // 1.57 Mbps default rate from CS:GO
net_splitpacket_maxrate 196608
net_splitrate 1 // How many packets to split per frame
net_maxcleartime 0.020346
mastercomfig seems to have several settings for the below but I picked out the "balanced" ones for you.
net_maxroutable 1200
net_maxfragments 1200